Kindly Delete your Cleo's and Mods if you have any.
2- If you're talking about the crash which appears in the starting of the game,Then Follow all these steps ,I've listed below:
Goto "My Documents">>than "Gta User Files>>Delete a file named as "Gta_Set".After deleting it,Try to relog.It might work.
I'd suggest you to explain deeply on whats causing the game to crash and why it crashes, does it crash on a specific location or its always crashing randomly? Please explain more deeply so we could get you a better solution. Thank you and good luck!